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Quartz Cuvettes and Cells – Exploring the Types

Cuvettes and optical cells are cornerstones of spectroscopic and analytical experiments. Whether you’re measuring UV-Vis absorbance, monitoring fluorescence, analyzing kinetics in real time, or working with reflection-based setups—the right sample cell makes all the difference.

💡 Your cuvette isn’t just a container. It’s a critical component that can define the accuracy and success of your entire workflow.

VFSM52 3.5mL Standard Fluorescence Cuvette with Inner Screw Cap Molded New Lighpath 10mm 2
Screw Cell
VFOMQ 3.5mL Fluorescence Cuvette with PTFE Lid Molded Flat Base Lighpath 10mm 1
4 Window Cell
VNE029 3.5mL IR Fluorescence Cuvette with Screw Cap 6
Standard Cell
VAOFL1 3.5mL Absorption Cuvette with Volume Markings PTFE Lid Fused Round Base Lighpath 10mm 1
Cell with Markings

🛠️ What This Guide Covers

This technical guide introduces the custom-fabricated cuvettes available from Qvarz, a leading provider of high-precision optical components.

You’ll get a deep dive into various cuvette categories—from everyday rectangular cells to highly specialized microvolume, flow-through, and demountable models.

Here’s what to expect:

  • 🔍 Key design and optical performance highlights
  • 🎯 Application-specific advantages
  • 🧩 Customization capabilities and engineering strengths
  • 🧪 Instrument compatibility (spectrophotometers, fluorometers, flow systems, and more)

❓ Can’t Find the Cuvette You Need?

Have a unique experimental setup that standard cuvettes won’t accommodate? Need a custom piece—fast and without outrageous costs?

You’re not the only one.

🚫 The problem: Many manufacturers prioritize mass production, leaving researchers stuck with long lead times and sky-high quotes for one-off orders.

🔧 The solution: Research isn’t one-size-fits-all. Qvarz specializes in crafting tailor-made cuvettes, even in small quantities, with fast turnaround and unmatched precision.

tailor made cuvettes for researchers

🌟 Why Choose Qvarz?

At Qvarz, we believe finding the perfect spectrophotometer cuvette should be simple—not a roadblock in your research.

Whether you’re:

  • Configuring a novel optical system,
  • Working with rare or sensitive microvolume samples, or
  • Seeking better control over background signal or flow dynamics…

…our team is here to design and deliver the cell that fits.

📦 Explore Your Options

👇 Scroll down to discover the full selection of Qvarz cuvette styles—many of which are in stock and ready to ship or customize.

From standard models to fully bespoke geometries, your ideal cuvette is just a few clicks away.


🔷 Standard Rectangular Cuvettes

Standard rectangular cuvettes are the workhorse of UV/Vis spectroscopy. Designed with two optically polished windows, they follow international dimensional standards and are compatible with nearly all spectrophotometers and fluorometers. The default path length is 10 mm, though options range from 1 mm to 100 mm to accommodate different concentration sensitivities.

VAOFIB 3.5mL Absorption Cuvette with PTFE Lid Fused Round Base Lighpath 10mm 2
2 Window Cuvette
VAPMG 3.5mL Absorption Cuvette with PTFE Stopper Molded Round Base Lighpath 10mm 3
Stopper Cuvette
VAPM6 0.35mL Absorption Cuvette with PTFE Stopper Molded Round Base Lighpath 1mm 1
1mm Cuvette
VAOF100 35mL Standard Absorption Cuvette with PTFE Lid Fused Lightpath 100mm 1
100mm Cuvette

These cuvettes are favored for their robust shape, versatility, and ease of use across routine absorbance applications. If you’re using path lengths beyond 10 mm, be sure to check your instrument’s specifications—larger sizes may need special holders or adapters.

🧾 Description

Rectangular cuvettes typically feature a square cross-section, a fixed 10 mm path length, and two clear optical windows (or four for fluorescence use). A standard 10 mm cuvette holds approximately 3.5 mL of sample. The outer dimensions (~12.5 × 12.5 mm) make them a universal fit for most instruments.

⭐ Key Features

  • Standardized Path Length & Size
    Industry-standard 10 mm optical path; available from ~1 mm to 100 mm. Compatible with most instruments.
  • High-Quality Optical Surfaces
    Made from UV, VIS, or IR-grade quartz or optical glass. Polished windows ensure accurate, low-distortion measurements.
  • Flexible Window Options
    Two-window models for absorbance; four-window models for fluorescence or cross-measurements.
  • Open or Sealed Tops
    Supplied with open tops (for stoppers/lids) or with screw caps for airtight handling.
Standard Rectangular Cuvettes Features

🏗️ Fabrication & Customization

  • Precision-Made Optical Paths
    Tight tolerance (±0.01 mm) ensures reproducibility. Optical faces are finely ground and polished.
  • Seamless Construction
    High-end cuvettes are fusion-bonded or molded from a single piece of quartz—no adhesives—making them chemically inert and heat-resistant (up to 600–1200 °C for quartz).
  • Tailored Designs Available
    Qvarz can customize dimensions, volumes, materials (e.g., IR-grade quartz), while keeping the outer footprint unchanged for compatibility.
Fabrication Customization

🔬 Common Applications

  • UV/VIS Absorbance
    Ideal for standard absorbance assays (DNA, proteins, chemicals). The 10 mm path provides a reliable baseline for most readings.
  • Fluorescence
    Four-window quartz cuvettes enable side-entry and right-angle detection—perfect for fluorometric setups.
  • General Lab Use
    Suitable for colorimetry, turbidity, and general liquid analysis. Quartz is compatible with most solvents and chemicals.

🧪 Instrument Compatibility

  • Universal Fit
    Designed for 1 cm holders, these cuvettes align with international spectrophotometer specs and fit most commercial systems.
  • Path Length Options
    Longer path cuvettes (20, 50, 100 mm) can enhance sensitivity but may require adapters. The standard 10 mm size fits directly without extra hardware.

🔷 Short Height Cuvettes

Short height cuvettes are compact rectangular cells with a reduced overall height, typically ranging from 10 mm to approximately 48 mm. They maintain the standard 10 mm optical path length but use less vertical space and require smaller sample volumes. This design lowers the Z-height—the vertical position of the optical center—making these cuvettes ideal for instruments with low beam heights or restricted vertical clearance.

🧾 Description

These cuvettes function like standard rectangular cells but in a smaller form. Despite their reduced height, they preserve the full 10 mm path length and standard square cross-section, ensuring optical consistency. The smaller internal volume is especially useful for conserving valuable or limited samples.

⭐ Key Features

  • Reduced Height Profile
    Designed for setups with limited vertical space. The cell body only extends slightly above the beam path, minimizing unnecessary volume.
  • Lower Sample Volume
    Requires significantly less liquid to fill. A short 10 mm cuvette may hold under 2 mL, in contrast to 3.5 mL in standard versions.
  • Standard Optical Path
    Maintains a 10 mm path length with high optical clarity. Some models use a “flush window” design, where nearly the entire height corresponds to the optical path, ideal for very small sample fills.

🏗️ Fabrication & Customization

  • Precise Z-Height Alignment
    Manufacturing focuses on accurately positioning the window center to match the light beam in instruments with low optical heights. Qvarz offers custom Z-dimensions tailored to instrument requirements.
  • High-Quality Assembly
    Due to their compact size, short cuvettes are built to tighter tolerances. Qvarz uses fusion bonding and fine polishing to ensure optical clarity, leak-proof performance, and chemical resistance.
  • Optional Closures
    While many short cells are open-top, they can be equipped with small PTFE lids or caps to minimize evaporation or contamination, even in tight spaces.

🔬 Typical Use Cases

  • Micro-Volume Spectrophotometry
    Perfect for portable or benchtop devices with small sample compartments. Also used in integrated systems like microscope-based spectrometers.
  • Limited-Sample Applications
    In fields like biochemistry or drug testing, where only small volumes are available, short cells enable accurate analysis without wasting sample.
  • Low Beam Height Instruments
    Tailored for instruments where the light path is close to the base. These cuvettes ensure the beam intersects the optical window without needing adjustable holders.
shor height cuvettes typical use cases

🧪 Instrument Compatibility

  • Specialized Holders or Inserts
    Standard holders may not accommodate the shorter height. Many instruments support short-cell adapters or inserts. Qvarz designs its short cuvettes to fit such systems.
  • Beam Alignment Considerations
    Light must pass through the clear window. These cuvettes align with common beam heights such as 8.5 mm or 15 mm, typical in compact spectrophotometers. Users should verify beam position to ensure proper fit and function.

🔷 Small Footprint Cuvettes

Small footprint cuvettes are designed with a reduced base area, typically smaller than the standard 12.5 × 12.5 mm square. A typical example might have a 10 × 10 mm cross-section, offering the same 10 mm path length but in a more compact form. These cuvettes are especially useful in space-limited setups or when working with instruments that accommodate multiple cells at once. Despite their smaller outer dimensions, they often retain full optical performance through thinner walls or narrower inner chambers.

🧾 Description

These cuvettes maintain standard path lengths while taking up less space. Their smaller cross-section makes them ideal for crowded setups, portable instruments, or custom holders where standard-sized cuvettes are too large. A typical 10 mm path small-footprint cell holds around 2–3 mL instead of the standard 3.5 mL.

⭐ Key Features

  • Compact Cell Body
    Smaller width and depth (e.g., 10 mm × 10 mm), making them suitable for narrow holders or setups with limited spacing.
  • Reduced Sample Volume
    Lower volume for the same path length saves sample material, much like semi-micro cuvettes.
  • Improved Rack Stability
    The compact design can offer better weight distribution and stability, though care should be taken to prevent tipping in some holders.
  • High-Quality Optical Windows
    Optical surfaces remain clear and precise, even if slightly reduced in size, and transmit the full light beam required for accurate readings.
small footprint cuvettes

🏗️ Fabrication & Customization

  • Thin-Wall Precision
    Thinner walls require advanced polishing and grinding. Qvarz ensures even the reduced material maintains optical quality and mechanical strength.
  • Seamless or Bonded Construction
    Options include molded one-piece quartz designs or precision-bonded pane construction. Qvarz also customizes dimensions for instrument-specific holders.
  • Adapters and Sleeves
    For use in standard holders, Qvarz offers adapters that securely house the small cuvette, aligning it properly within a 12.5 mm cell slot.

🔬 Typical Use Cases

  • Multi-Cell Instruments
    Useful in autosamplers or multi-position carousels, allowing more cuvettes to fit in parallel for higher throughput.
  • Portable and Field Instruments
    Ideal for handheld devices where size and weight are critical, supporting on-site testing or compact analytical equipment.
  • Benchtop Space Optimization
    Suitable for dense layouts like temperature-controlled assay blocks, where smaller cuvettes improve space efficiency and thermal distribution.

🧪 Instrument Compatibility

  • Custom Holders or Inserts
    Designed for specific systems like the Malvern Zetasizer or plate readers. Adapters are often needed for use in traditional 1 cm square spectrophotometer slots.
  • Beam Alignment Requirements
    The slightly smaller window must be properly centered. When aligned, performance is equivalent to standard cuvettes, but users should ensure the instrument beam fully covers the optical area to avoid distortion or loss of signal.

🔷 Detachable Cuvettes

Detachable cuvettes, also called demountable or assembled cuvettes, are multi-part cells that can be taken apart for cleaning, modification, or sample insertion. Unlike sealed one-piece cuvettes, these consist of two or more components—often two quartz halves joined by screws, clamps, or sleeves. When reassembled, they function as sealed cuvettes with a defined path length.

🧾 Description

These cuvettes are ideal for scenarios where internal cleaning is essential or where custom configurations are needed. Users can access all internal surfaces, change windows, or insert challenging sample types. Despite their modular nature, once assembled, they behave like conventional cuvettes in terms of optical performance.

⭐ Key Features

  • Two-Part Construction
    Made from two precisely matched halves, sealed with gaskets or O-rings and secured with screws or clamps for leak-proof performance.
  • Optional Adjustable Path Length
    Some designs allow for interchangeable spacers or gaskets to vary the path length—useful in IR applications where flexibility is needed.
  • Ease of Cleaning
    Easily disassembled for thorough cleaning of all internal surfaces, especially helpful with sticky or residue-prone samples.
  • Modular Windows
    Compatible with different window materials (e.g., CaF₂ for IR, quartz for UV), allowing the same body to serve multiple purposes.
detachable cell features

🏗️ Fabrication & Customization

  • Precision-Machined Interfaces
    The mating surfaces are flat and parallel to optical tolerances. Qvarz machines each part to ensure precise sealing and beam alignment.
  • Chemical-Resistant Seals
    Uses high-grade gaskets (e.g., PTFE or solvent-resistant materials) that tolerate the required conditions without leaking or degrading.
  • Custom Designs
    Options include demountable flow cells, multi-window fluorescence designs, or variable-path cells. Window sets and spacers can be customized per user needs.
  • Secure Assembly Hardware
    Screws or clamps are designed to apply even pressure without distorting the optical path. Qvarz ensures all fastening mechanisms are aligned and smooth for safe tightening.

🔬 Typical Use Cases

  • IR Spectroscopy
    Frequently used in FTIR applications with removable salt windows that must be cleaned or replaced between samples.
  • Challenging Sample Types
    Ideal for viscous or particulate samples that are difficult to clean out of sealed cuvettes—common in protein, polymer, or lipid research.
  • Custom Path Length Studies
    Enables quick testing across multiple optical path lengths by changing spacers instead of switching cuvettes.
  • Fluorescence with Inserts
    Allows internal placement of probes, sensors, or other inserts for specialized experiments. The cell is closed around the accessory for a secure and sealed fit.
detachable cell use cases

🧪 Instrument Compatibility

  • Standard Holder Fit (Assembled)
    When fully assembled, detachable cuvettes typically match standard 12.5 mm × 12.5 mm dimensions, fitting standard holders unless custom-sized.
  • Handling and Clearance
    Slightly bulkier due to screws or clamps, so care is needed in tight instrument chambers. Not usually compatible with automatic changers.
  • Leak Prevention
    Proper assembly is essential to avoid leaks or window fogging. When correctly sealed, performance is equivalent to one-piece cuvettes in manual-use spectrometers.

❓ How Do You Assemble a Detachable Cuvette?

Assembling a detachable (demountable) cuvette correctly is essential for leak-free operation and accurate measurements. Here’s how to do it:

✅ Step-by-Step Assembly Instructions

  1. Inspect All Components
    Ensure all parts are clean and undamaged:
    • Cell body halves
    • Optical windows (if separate)
    • Gasket or spacer (usually PTFE, silicone, or solvent-resistant material)
    • Screws or clamps
  2. Place the Gasket or Spacer
    Position the gasket or path length spacer between the two halves. Ensure it is flat and centered to avoid uneven pressure or leaks.
  3. Insert Windows (if separate)
    If your design includes removable windows, carefully insert them into the designated grooves or slots. Make sure they are seated evenly.
  4. Align the Halves
    Bring the two halves of the cuvette together, aligning the edges precisely. The optical faces must be parallel and fully in contact with the gasket.
  5. Tighten Screws or Clamps Evenly
    Begin tightening the screws or clamps in a diagonal or alternating pattern to ensure even compression. Do not overtighten—apply just enough pressure to seal the cell without warping the components.
  6. Check the Assembly
    Hold the cuvette up to a light source. The windows should appear clean and properly aligned. There should be no gaps, tilts, or visible distortion.
  7. Test for Leaks (Optional but Recommended)
    Before filling with sample, you can test the assembled cuvette using distilled water to ensure it’s sealed. Place a tissue around the joints and check for moisture after a few minutes.
detachable cell assembly

🛠️ Tips for Best Results

  • Use clean gloves or tweezers to handle windows and gaskets—fingerprints can interfere with optical readings.
  • Avoid overtightening, especially with quartz windows, to prevent cracking.
  • Keep spare gaskets in different thicknesses if you plan to adjust the path length frequently.
  • If using removable windows, do not mix sets between different cuvettes to maintain fit and alignment.

Proper assembly ensures that your detachable cuvette delivers the same optical performance as a sealed unit, with the added benefits of flexibility, cleanability, and customizability.


🔷 Bubble-Free Cuvettes

Bubble-free cuvettes are specialized flow-through cells designed to eliminate trapped air bubbles during continuous liquid flow. Bubbles in the optical path can cause signal noise, erratic absorbance values, and baseline drift. These cuvettes feature unique internal geometries and connector placements—such as vertical flow orientation or funnel-shaped channels—that allow air to escape upward while keeping the optical zone fully filled with liquid for uninterrupted, high-precision measurements.

🧾 Description

By utilizing strategic inlet and outlet positioning and smoothed flow channels, bubble-free cuvettes ensure consistent fluid contact with the optical windows. The result is stable and accurate readings even during rapid flow or sample switching, making them ideal for automated and continuous-monitoring applications.

⭐ Key Features

  • Funnel or Vertical Channel Geometry
    Designed to direct bubbles away from the optical zone. Fluid typically enters from the bottom and exits from the top, carrying bubbles upward and out of the cell.
  • Top-Side Connectors
    Both inlet and outlet are often positioned on top, with one extending internally to reach the cell base—this upward flow removes trapped air efficiently.
  • Smooth Interior Surfaces
    Polished, corner-free channels reduce bubble formation sites and help gas escape naturally, minimizing interference.
  • Defined Optical Path
    Maintains a precise path length (1–10 mm) across clear, parallel windows. Optical behavior is identical to standard cuvettes.
  • Durable Construction
    Typically made from fused quartz for chemical resistance and thermal stability—suitable for aggressive solvents and high temperatures (up to 1200 °C).

🏗️ Fabrication & Customization

  • Integrated Connectors
    Inlets and outlets are fused or bonded directly into the quartz body. Common options include barbed, threaded, or Luer-lock styles. Joints are seamless to avoid leakage or bubble traps.
  • Optimized Internal Geometry
    Qvarz customizes flow channels to support smooth, bubble-free liquid motion. Modifications include widened chambers, sloped ceilings, or angled inlets for degassing.
  • Optical-Grade Polishing
    Flow chambers are polished to reduce light scatter and improve flow uniformity. This also limits bubble retention at the channel walls.
  • Custom Options Available
    Path length, body size, connector type, and mounting shape can all be adapted to fit user setups—from microfluidic instruments to bench-top analyzers.

🔬 Typical Use Cases

  • HPLC UV Detection
    Prevents baseline disruption in high-throughput liquid chromatography systems where air bubbles from the pump or eluents are common.
  • Flow Injection Analysis (FIA)
    Critical for automated mixing and detection systems where precision is vital and stopping for degassing is impractical.
  • Biotech Fermentation Monitoring
    Enables real-time OD₆₀₀ measurements of culture broth without bubble-induced signal spikes.
  • Aqueous and Solvent Circulation Systems
    Used in environmental analyzers, process instruments, or water-quality monitors where bubbles may form due to pump motion or dissolved gas release.
bubble free cuvette use cases

🧪 Instrument Compatibility

  • Flow Cell-Ready Holders
    Fits spectrometers with external flow cell attachments. Qvarz bubble-free cells match standard sizes for easy integration into most lab systems.
  • Standard Plumbing Connections
    Compatible with common fittings, Luer, or barbed ends. Ready for direct connection to peristaltic pumps, autosamplers, or HPLC systems.
  • Vertical Orientation Required
    To function correctly, these cuvettes must be mounted vertically. Most lab spectrophotometers support vertical orientation via accessories or custom stands. Once installed, they function optically like a standard cuvette—minus the bubble disruptions.

🔷 Flow Through Cuvettes with Top Connectors

Flow-through cuvettes with top connectors are specialized continuous-flow cells where both the inlet and outlet are located on the top of the cuvette body. This design directs fluid from the bottom to the top inside the cell, ensuring effective flushing of air bubbles and consistent filling of the optical chamber. These cuvettes are commonly used for real-time monitoring of flowing samples and are particularly effective in automated or pressurized systems. They share many principles with bubble-free cuvettes but are specifically designed for vertical, upward fluid motion.

🧾 Description

These cuvettes have transparent side windows for optical measurement while the fluid flows vertically through the chamber. A tube inserted through the inlet port reaches the bottom of the cell, introducing sample from below and pushing existing fluid upward and out through the outlet. This method maintains a bubble-free optical path and allows the sample to be continuously monitored as it flows through.

⭐ Key Features

  • Top-Mounted Inlet and Outlet
    Fluid enters from the bottom (via an internal feed tube) and exits at the top, allowing upward flushing of bubbles and full optical coverage.
  • Vertical Flow Orientation
    Fluid movement is from bottom to top, while light passes horizontally through the vertical walls of the cell for real-time absorbance readings.
  • Sealed Top Plate
    The top ports are securely sealed using O-rings or ferrules. The design prevents leakage and allows safe operation under pressure.
  • Standard Optical Geometry
    Provides precise path lengths (1, 5, 10 mm typical), with optical windows placed below the inlet/outlet level to avoid interference.
flow through cuvettes with top connectors features

🏗️ Fabrication & Customization

  • Drilled or Molded Quartz Top Plate
    The inlet/outlet ports are machined or molded into a quartz top, fused to the cell body. Internal feed tubes are aligned to avoid blocking the optical window.
  • Internal Flow Optimization
    Some designs include a funnel-shaped or sloped interior to guide fluid flow evenly. Port spacing on the top can be customized for different tubing setups.
  • Threaded or Fused Connectors
    Connectors may be PTFE, PEEK, or all-quartz, chemically resistant and pressure-rated. Qvarz ensures leak-tight sealing and durable fittings for secure fluid handling.
  • Custom Dimensions and Volumes
    Cells can be built to specific internal volumes or flow rates. Taller cells for slower flow, or wider ones for high-volume throughput, are available on request.

🔬 Typical Use Cases

  • Real-Time Reaction Monitoring
    Monitor chemical reactions continuously by circulating the mixture through the flow cell. Upward flushing removes gas bubbles formed during the reaction.
  • Auto-Sampler Integration
    Works seamlessly with automated systems that inject samples in succession. The new sample displaces the previous one without air pockets or residual contamination.
  • Biochemical Flow Assays
    Suitable for enzyme kinetics, DNA hybridization, or reagent mixing where buffer/sample/wash solutions need to pass through the same optical cell continuously.
  • Process or Field Monitoring
    Used in portable or fixed industrial analyzers to monitor water quality, chemical content, or pollutants in real time via vertical piping systems.
flow through cuvettes with top connectors applications

🧪 Instrument Compatibility

  • Spectrophotometers with Flow Adapters
    Compatible with many modern spectrometers using flow cell holders. Top ports may require the lid to remain open or a modified sample chamber with tubing access.
  • External Fiber-Optic Mounting
    Often used with instruments that send/receive light via fiber optics. These cells are mounted vertically, with light passing through side windows via fiber couplers.
  • Flow and Pressure Management
    Suited for moderate flow rates and pressures typical of HPLC, FIA, or syringe pump systems. High-pressure applications may need reinforced or specialized versions, which Qvarz can provide.

🔷 Long Mouth Cuvettes

Long mouth cuvettes are specialized rectangular cells with an extended neck or tubular section above the optical chamber. This “mouth” is often a fused quartz tube, straight or Y-shaped, that significantly increases the cuvette’s overall height—typically reaching 90–135 mm compared to the ~45 mm height of standard cells. While the optical path remains fixed in the lower part of the cell (e.g., 10 mm), the extended neck allows for enhanced handling, secure sealing, larger sample capacity, and insertion of external accessories like electrodes, thermometers, or reagent additions.

🧾 Description

The extended top section enables applications that require sealed environments, additional sample volume, or real-time manipulation (e.g., adding reagents or inserting sensors) during optical measurement. The light path remains in the standard vertical location to ensure instrument compatibility.

⭐ Key Features

  • Extended Tubular Neck
    A long neck extends vertically from the cuvette body. Variants include single straight tubes or dual-neck (Y-shaped) designs, used for multi-channel access.
  • Larger Sample Volume
    With the added neck volume, a long mouth cuvette can hold 5–10 mL or more, compared to the ~3.5 mL of standard 10 mm path cuvettes.
  • Sealable Top
    Threaded or stoppered openings allow secure sealing with PTFE or PEEK caps, often with septa for syringe access or inert gas protection.
  • Accessory Compatibility
    The extra neck space accommodates stirring rods, thermocouples, gas lines, or injection needles—without interfering with the optical beam path.
Long Mouth Cuvettes Features

🏗️ Fabrication & Customization

  • Fused Quartz Neck Construction
    The neck is precision-fused to the cuvette body with proper centering and vertical alignment. Joints are annealed for strength and chemical durability.
  • Threaded Cap Options
    Qvarz can grind internal or external threads on the neck, matched with chemical-resistant screw caps and sealing O-rings or gaskets.
  • Y-Shaped Necks
    Optional dual-neck designs enable simultaneous reagent addition and sensor insertion. Both necks are symmetrically fused for balance and instrument clearance.
  • High Durability
    All-quartz contact surfaces tolerate solvents, acids, and high heat (rated to ~1200 °C). The neck won’t crack under normal heating/cooling due to proper thermal treatment.

🔬 Typical Use Cases

  • Fluorescence of Sealed or Volatile Samples
    Ideal for fluorescence measurements of air-sensitive or evaporative solutions. The cap prevents air exchange while maintaining optical performance.
  • Long-Term Kinetics
    Used in multi-hour or multi-day reactions, these cuvettes prevent evaporation, contamination, or sample oxidation.
  • Titrations or Reagent Injections During Measurement
    Reagents can be added via syringe through a septum while the cell remains in the instrument. The long neck serves as a reaction funnel.
  • Temperature-Controlled Experiments
    Compatible with water-jacketed holders. The long neck allows insertion of thermometers while keeping the optical section submerged.

🧪 Instrument Compatibility

  • Spectrometer Holder Fit
    The base footprint remains standard (typically 12.5 × 12.5 mm), fitting into conventional cuvette holders. The light path position is unchanged.
  • Vertical Clearance Requirements
    Due to their height, long mouth cuvettes may not fit inside enclosed compartments with the lid closed. Many users operate them with the lid open, under a dark enclosure or lab hood.
  • Safe Handling
    Their tall structure can be top-heavy. Qvarz recommends using holders with added support or guide holes. Y-shaped designs are angled to avoid interference with clamps or springs.
  • External Accessory Integration
    Compatible with fiber optic probes, electrodes, or other analytical tools that insert through the neck while leaving the optical windows unobstructed. Perfect for hybrid spectro-electrochemical setups or dynamic monitoring.

🔷 Wide Window Cells

Wide window cells are cuvettes engineered with extra-large optical windows that far exceed the standard 10 mm width. These enlarged windows—ranging from 20 mm to 50 mm or more—enable broader light transmission and are typically paired with larger-volume macro cells. The design is especially useful in experiments where higher optical throughput is needed, such as with dilute samples, expanded light beams, or multi-angle optical systems.

🧾 Description

Unlike standard cuvettes, which have small, fixed-size windows, wide window cells offer a broader cross-section for light to pass through the sample. While the path length (e.g., 10 mm) remains standard, the widened windows allow for more extensive illumination and a greater interaction volume, improving sensitivity and light collection in suitable instruments.

⭐ Key Features

  • Enlarged Optical Aperture
    Windows can be 20–50 mm wide or more, matching expanded beam widths or allowing high-throughput detection in customized instruments.
  • High Sample Volume
    Larger interior dimensions mean more liquid in the light path. This improves signal strength when working with low-concentration samples.
  • Macro Path Options
    Available in extended path lengths such as 20 mm or 50 mm, combined with wide windows to optimize absorption for ultra-dilute solutions.
  • Multi-Angle Observation
    Some versions include up to four wide windows, enabling fluorescence detection or light scattering measurements at multiple angles.

🏗️ Fabrication & Customization

  • Large Quartz Window Panels
    Wide optical windows require optically flat, high-purity quartz. Qvarz carefully polishes these to maintain clarity and thickness uniformity across large surfaces.
  • Reinforced Construction
    Wider surfaces are structurally supported with thicker side walls or fused reinforcing strips to prevent flexing or bowing when filled with liquid.
  • Precision Bonding
    Qvarz uses advanced fusion or high-grade adhesive techniques to secure large panels while ensuring full-perimeter sealing and leak-proof performance.
  • Custom Window Dimensions
    Windows can be tailored to match beam size or camera field of view, with adjustable height and width for both horizontal and vertical illumination setups.

🔬 Typical Use Cases

  • Low-Concentration Sample Detection
    Ideal for trace-level analysis (e.g., environmental pollutants, chlorophyll, metal ions), where more light/sample interaction boosts sensitivity.
  • Photometric Calibration
    Used in calibration protocols or titrations requiring a wide light path to ensure full beam coverage and minimize edge effects.
  • Turbidity and Scattering Studies
    Wider windows improve signal collection for scattering angles, enhancing measurements in turbid or colloidal samples.
  • Preparative and Large-Scale Analysis
    Supports large sample volumes in preparative or scale-up testing where dilution or repeated small-sample loading is impractical.
wide window cells capplications

🧪 Instrument Compatibility

  • Requires Specialized Holder
    These cells won’t fit standard 1 cm slots and must be mounted in custom holders, external brackets, or optical rail systems.
  • Beam Size Match Needed
    Must be used with instruments featuring wide or adjustable beams. Otherwise, only a portion of the window is illuminated, reducing the benefit of the design.
  • Secure Mounting Required
    Wide window cells are heavier and may require clamps or dedicated mounts to stay level and aligned, especially when filled with liquid.
  • Standard Path Alignment
    Despite their size, the optical path remains centered. Instruments with adjustable beam height/width can align easily to the larger window region, ensuring full use of the optical area.

🔷 Large Tank Cells

Large tank cells are oversized cuvettes with an open top and multiple transparent sides—typically all four vertical walls and the bottom—creating five optical windows. These cells resemble small tanks or aquariums and are designed for experiments requiring large sample volumes, multi-angle optical access, or the ability to insert equipment directly into the sample. They are fully customizable in shape, volume, and features, making them suitable for specialized optical or chemical experiments.

🧾 Description

Unlike conventional cuvettes with fixed geometry, large tank cells offer open-format flexibility. The optical path is determined by how the cell is oriented and used. They provide ample space for laser-based experiments, photochemistry, or optical monitoring of dynamic processes, while maintaining optical-grade clarity on all visible sides.

⭐ Key Features

  • 5-Sided Optical Access
    Four clear side walls and a transparent bottom allow for horizontal, vertical, or angled light paths. Suitable for absorbance, fluorescence, scattering, or imaging applications.
  • High Volume Capacity
    Standard volumes range from 15 mL to over 100 mL. Example: a 50 mm × 50 mm × 50 mm tank holds ~125 mL. Ideal for reactions, titrations, or bulk sample testing.
  • Open Top for Interaction
    The open format supports easy addition of reagents, stirrers, sensors, or electrodes. Perfect for long-term kinetics or free-surface studies.
  • Custom Path Orientation
    Since the cell has no fixed light path, users can measure through any pair of opposing faces. Useful for flexible experiment configurations.
  • Customizable Dimensions and Covers
    Qvarz can fabricate large tank cells to exact user specifications—height, width, and depth can be customized to fit experimental needs. Optional quartz lids or PTFE covers are available to minimize evaporation, exclude dust, or control atmosphere.
large tank cell features

🏗️ Fabrication & Customization

  • Precision Plate Assembly
    Made from optically polished quartz plates bonded or thermally fused into a rectangular tank. Joints are clean and leak-tight.
  • Reinforced Corners and Edges
    Structural integrity is enhanced by beveling edges, using thicker quartz, or integrating internal support rods at corners. For very large tanks, external frames can be added.
  • Uniform Clarity and Thickness
    All panels are matched for thickness and flatness. Surfaces are polished on both sides to eliminate distortion, bubbles, or striations.
  • Custom Ports and Features
    Qvarz offers drilling and port integration for side access, drainage, or probe insertion. Custom features such as black background strips, internal guide markings, or overflow channels can be added.
  • Custom Lids Available
    Optional flat quartz lids or chemically resistant PTFE covers can be provided. Lids may be loose-fitting or sealed, depending on application.

🔬 Typical Use Cases

  • Laser and Fluorescence Studies
    Multiple clear sides allow for simultaneous illumination and detection from different angles—perfect for advanced laser setups or fluorescence imaging.
  • Photochemistry and UV Reactions
    Large exposed surface area allows effective irradiation from lamps or light boxes. Ideal for solar simulation or UV degradation studies.
  • Titration and In-Situ Mixing
    Reagents can be added directly during measurement. The large volume accommodates mixing without disturbing optical paths.
  • Combined Spectroscopy and Imaging
    The open top allows camera or microscope access while side windows provide light transmission for spectrophotometric data collection.
large tank cell use cases

🧪 Instrument Compatibility

  • Not Compatible with Standard Holders
    Too large for typical cuvette compartments. Used on optical benches, lab jacks, or in custom enclosures with external light sources and detectors.
  • Fiber Optic Use Supported
    Fiber probes can be placed on opposite windows for in-line light transmission and collection. This allows use with standard spectrometers via fiber-coupled input/output.
  • Custom Holder Options
    For smaller tanks, custom holders or brackets can be designed to fit within instrument compartments. Qvarz can coordinate sizing to match specific devices.
  • Ambient Light Control Required
    Due to all-clear construction, open-air use must be shielded from stray light. Use in dark rooms or enclosures is recommended for accurate readings. Lids can help reduce exposure and contamination.

🔷 Flow Cuvettes with Side Connectors

Flow cuvettes with side connectors are continuous-flow cells designed with inlet and outlet ports located on the sides of the cuvette body. These ports are typically positioned opposite each other or offset on the same side, allowing liquid to flow horizontally through the cell. While the fluid enters from one side and exits from the other, light passes through front and back optical windows—creating a clean separation between fluid routing and optical measurement. This format is compact, compatible with standard spectrophotometers, and well-suited for systems with limited vertical space.

🧾 Description

Side-connected flow cuvettes are ideal for horizontal mounting or for spectrometer compartments where vertical tubing access is impractical. They are commonly used in HPLC detection, process monitoring, and automated analytical platforms, offering flexibility and easy integration into flow systems. Their design supports precise flow across the optical zone while keeping the top of the cell free for other functions.

⭐ Key Features

  • Side-Mounted Inlet/Outlet Ports
    Fluid flows laterally through the cell, crossing the optical measurement zone between opposing or offset side connectors.
  • Defined Horizontal Flow Path
    Enables consistent cross-chamber flow that complements instruments with horizontal light beams. Some configurations use slight height offsets to assist with bubble removal.
  • Compact and Instrument-Friendly
    With no top-side fittings, these cells fit into standard holders with closed lids—an advantage in instruments that require a sealed measurement chamber.
  • Standard Optical Geometry
    Clear quartz windows ensure a defined path length (commonly 10 mm), allowing accurate UV-Vis or fluorescence readings in real-time flow mode.

🏗️ Fabrication & Customization

  • Precision Side Arm Integration
    Connectors are bonded or fused into the quartz side wall, carefully placed outside the optical window region. Drilled holes are sealed with high precision to avoid leaks or stress points.
  • Smooth Internal Flow Channels
    Flow paths are polished and streamlined to reduce turbulence, avoid trapping bubbles, and support stable laminar flow.
  • Connector Variety and Orientation
    Available with Luer-lock, barbed, or threaded ports (e.g., 1/16″ or 1/8″ compression). Qvarz adjusts positioning and orientation based on your system’s tubing and direction needs.
  • Custom Flow Geometry
    Ports can be placed opposite or offset, at different heights or angles, to match instrument architecture or optimize bubble evacuation.
flow cell customization

🔬 Typical Use Cases

  • HPLC UV-Vis Detection
    Standard in many chromatography systems—flow from one side to the other through the optical chamber allows precise monitoring of eluents in real time.
  • Inline Process Monitoring
    Integrated into industrial or laboratory pipelines as bypass measurement chambers for checking color, turbidity, or absorbance.
  • Plate Readers and Automation Platforms
    Used in instruments where top access is restricted; tubing routes laterally, allowing integration into compact or robotic systems.
  • Flow Fluorescence Applications
    Keeps the top of the cuvette clear for fiber optic probes or fluorescence excitation light while fluid enters from the side, avoiding shadowing or interference.

🧪 Instrument Compatibility

  • Fits Standard Cuvette Holders
    Designed with the same external dimensions as standard 10 mm cuvettes (excluding side ports), they slot into most spectrophotometer holders without modification.
  • No Vertical Clearance Needed
    Side connections eliminate the need for vertical tubing, allowing lids to close fully. Ideal for instruments that restrict operation with open lids.
  • Beam Path Unobstructed
    Qvarz ensures that side connectors are offset vertically from the beam path to prevent interference. Proper insertion keeps fittings out of alignment with the light beam.
  • Custom Flow Direction Support
    Configurable for bottom-to-top or crosswise flow depending on bubble management needs. Users can select the inlet and outlet positions to best support their fluid system’s pressure and degassing characteristics.

These cuvettes combine high compatibility with excellent fluid handling performance and are a practical choice for most flow-based spectroscopic systems.


🔷 Customized 2 Ends Open Cuvettes

Customized 2 ends open cuvettes are specialized optical cells that are open at both the top and bottom—forming a vertical flow channel with transparent sides. Unlike traditional cuvettes that are sealed at the bottom, these designs allow fluid to enter and exit freely from either end. They are commonly used in custom flow systems, gravity-fed analyzers, and inline monitoring setups. Made to order, these cuvettes are built around specific dimensions, optical paths, and integration needs.

🧾 Description

These cuvettes function like open tubes with optical-grade windows along two (or more) sides. Fluid flows vertically through the cell, and measurements are taken as the sample moves past the optical window zone. Their open-ended structure allows them to be placed directly into a flow loop or dipped into a sample container for on-the-spot readings.

⭐ Key Features

  • Open Vertical Channel
    Fluid flows freely through both open ends—ideal for gravity-fed or vertical flow-through designs.
  • Optical Side Windows
    Clear windows on opposing walls allow horizontal light transmission. Optional 4-window versions support fluorescence or multi-angle detection.
  • Custom Path Length and Cross-Section
    The distance between windows defines the optical path (e.g., 2 mm, 5 mm, 10 mm), while the overall height and cross-section can be tailored to the application.
  • Mounting Flanges or Shoulders
    Optional flanges or rims can be added to allow the cell to seat in O-ring gaskets, clamps, or flow housings without leaking.
  • Tube or Frame Design
    Cells may be constructed as rectangular tubes from quartz panels or as modified circular tubes with optical cutouts.
2 ends open cuvette features

🏗️ Fabrication & Customization

  • Precision-Fused Construction
    Made from optically polished quartz plates or tubing, fused into a seamless tube. Ends are fire-polished or beveled to remove sharpness and aid sealing.
  • Flat, Parallel Windows
    Optical faces are polished to high flatness for clean, distortion-free measurements. End surfaces are ground flat if used with sealing gaskets.
  • Flexible Dimensions
    Users can specify the path length, height, and outer dimensions. Example: a 3 mm path, 50 mm tall cell with open ends and 4 clear sides.
  • Optional Add-ons
    Qvarz can add flanges, collars, or even connector mounts to integrate the cell into a flow chamber. Multiple optical windows or custom window heights can also be fabricated.

🔬 Typical Use Cases

  • Vertical Flow Systems
    Used in gravity-driven analyzers or vertical flow cells where samples pass through the cuvette by gravity or minimal pressure.
  • Inline Process Monitoring
    Acts as a viewing window in a bypass or inline flow loop. Fluids are directed through the cuvette for real-time spectroscopic analysis.
  • Dip-In Sampling
    Used like a dip probe—immersed into a tank or beaker to take quick optical measurements directly without extracting the sample.
  • Sensor and Bioreactor Integration
    Can house membranes, sensors, or biological specimens that require continuous exposure to flowing fluids while being optically monitored.

🧪 Instrument Compatibility

  • Requires Custom Holders
    These are not compatible with standard sealed-bottom spectrometer holders. Typically used in flow modules or custom mounting systems with gaskets or clamps.
  • Compatible with Fiber Optic Systems
    Often used in setups where light is delivered and collected via fiber optics. External holders align the beam with the optical windows.
  • Orientation Flexibility
    Primarily vertical, but can be mounted horizontally with end sealing if needed. Mounting geometry is user-defined.
  • Seal-Ready Ends
    Ground or beveled open ends allow reliable sealing with O-rings or compression fittings when inserted into an external housing. Qvarz ensures dimensional consistency for leak-free integration.

Customized 2 ends open cuvettes are ideal for researchers and engineers developing bespoke optical or flow systems. Their open architecture and adaptable design make them highly versatile for creative scientific applications.


🔺 Triangular Cuvettes

Triangular cuvettes have a triangular base—either equilateral or right-angled—unlike standard square or rectangular types. They are widely used in front-face fluorescence applications, especially for highly absorbing or turbid samples. This design allows excitation light to enter at a 45° angle and emission light to be collected at 90°, reducing the optical path length and minimizing inner-filter effects. These cuvettes may be open-top or sealed with a PTFE stopper for volatile or sensitive samples.

⚙️ Key Features

  • Three-sided design with transparent quartz walls arranged in a triangular prism. Common configurations include equilateral triangles (60° angles) and right-angled triangles (45°/90°).
  • Optimized for front-face fluorescence, enabling shallow-angle excitation and side emission detection, especially useful for optically dense samples.
  • Shortened excitation path allows only a few millimeters of penetration, avoiding full 10 mm light paths that would otherwise absorb all excitation.
  • Stopper options are available. Many triangular cells include PTFE stoppers for airtight sealing or contamination prevention.
triangular cuvettes features

🛠️ Fabrication & Customization

  • Precision polishing and fusing ensure tight angle control and leak-free joints. Qvarz uses custom jigs to assemble triangular prisms with perfect optical alignment.
  • Adjustable path lengths are available, typically 10 mm standard, but custom sizes and shapes can be produced on request.
  • High-purity UV-grade quartz construction offers excellent chemical resistance and thermal stability (up to 600 °C).
  • Optional blackened wall can be applied to reduce stray light and enhance signal clarity when fewer than three optical faces are used.

🔬 Typical Use Cases

  • Fluorescence measurements of opaque samples, such as concentrated dyes, crude oil, or hemoglobin solutions, where standard cuvettes are unusable.
  • Scattering or turbid media, such as bacterial suspensions or emulsions, which benefit from the shallow light penetration of front-face geometry.
  • Specialized spectroscopic setups including fluorescence polarization, circular dichroism, or custom-built detection systems.
  • Multi-angle absorbance or refractive measurements, though less common, are possible thanks to the multiple optical access points.

🧪 Instrument Compatibility

  • Compatible with most fluorometers, particularly those designed for front-face geometry. Qvarz triangular cuvettes fit standard triangular or round holders.
  • Usable in absorbance spectrometers with caution—alignment and path length adjustments may be needed for accurate readings.
  • Orientation matters: users must place the cuvette correctly, usually with the excitation beam aimed at the 45° face.
  • Fits in standard 10 mm cell holders in most cases, though the triangular shape may be a snug fit. PTFE stoppers should be checked to ensure they do not obstruct detection pathways.

🧪 Special Custom Cuvettes

Special custom cuvettes are one-of-a-kind designs built to solve unique experimental challenges. Unlike standard or “non-stock customizable” options, these cuvettes often integrate advanced features like mirrors, filters, multi-chamber architecture, or novel geometries. If a scientist can imagine it, Qvarz can likely make it—by merging precision quartz craftsmanship with engineering expertise.

⚙️ Key Features

  • Multi-Chamber Designs: Separate compartments in one cell, with removable dividers for side-by-side measurements or in-cell mixing.
  • Built-in Optical Elements: Mirrors for double-pass paths, integrated prisms, diffraction gratings, or fiber optic couplings.
  • Unusual Shapes: From wedge-shaped to spherical or cylindrical with oblique flats, customized for advanced light paths.
  • Sensor Integration: Built-in electrodes for spectroelectrochemistry, or ports for pH, temperature, or conductivity probes.
  • Matched Calibration Cells: Sets of optically identical cuvettes or pre-tinted standards for reference measurements.
custom cuvettes

🛠️ Fabrication & Manufacturing Strengths

  • Collaborative Engineering: Qvarz works directly with users to translate experimental needs into practical, manufacturable designs.
  • Hybrid Techniques: Combining CNC machining, glassblowing, and optical polishing—even within one project.
  • High-Precision Testing: Every cell—especially those with complex geometry—is inspected and tested for leaks, optical alignment, and clarity.
  • Material Flexibility: Integration of metals (like Kovar), polymers, or fused seals into quartz cells to accommodate sensors or withstand extreme conditions.

🔬 Typical Use Cases

  • Spectroelectrochemistry: Dual-function cells that apply voltage while enabling spectroscopic readout.
  • Multi-Pass Laser Optics: Miniaturized Herriott cells that fold light paths with internal mirrors.
  • Dual-Mode Analysis: Cuvettes that enable both optical and NMR readings, or UV-Vis and chromatography simultaneously.
  • Education & Demonstration: Large or visually enhanced cuvettes for teaching optical concepts in the classroom.
  • Legacy Equipment Support: Replication of rare or discontinued cells to extend the life of older analytical instruments.

🧩 Instrument Compatibility

  • Made-to-Fit: Each custom cuvette is tailored to the user’s specific instrument, ensuring seamless integration.
  • Prototype & Iteration: Qvarz can prototype, fit-test, and refine before final production, especially for critical applications.
  • Instructional Support: Documentation is provided for complex assemblies or alignment procedures.
  • Modular Versatility: Some special cells are designed to be reconfigured—switching between single- or dual-use modes by adding/removing partitions.

These special custom cuvettes push the boundaries of what’s possible in lab instrumentation—turning bespoke ideas into durable, precise, and compatible optical tools.


🧪 Sub-Micro Cuvettes

Sub-micro cuvettes are ultra-low volume cells designed for measurements on extremely small sample quantities—ranging from sub-microliter volumes up to a few hundred microliters. Typically, “sub-micro” refers to volumes under 400 µL, with many designs accommodating as little as 50 µL or even 10 µL.

These cuvettes achieve minimal volume by reducing inner dimensions (narrower internal widths or shorter path lengths) and sometimes by integrating funnel-shaped tops or loading aids.

Despite the reduced sample volume, they still offer a defined optical path—often 10 mm or shorter—for accurate spectroscopic readings. These cuvettes are vital in fields such as molecular biology and pharmacology, where samples are scarce or expensive.

📌 Key Features

  • Very Low Sample Volume
    Sub-micro cuvettes can function with only a few dozen microliters of liquid. Common designs hold 100 µL, with some going down to 50 µL or 10 µL, depending on the geometry and path length.
  • Reduced Cross-Section or Path
    To minimize volume, sub-micro cuvettes often feature narrower internal widths (e.g., 2–4 mm) or shorter optical path lengths (e.g., 4 mm instead of the standard 10 mm). Some designs keep the standard external size but limit the usable volume by incorporating a narrow internal pocket while the rest of the interior is filled with solid quartz or light-blocking material.
  • Black Walls for Absorbance
    Many absorbance-specific sub-micro cuvettes have blackened walls except for the clear optical windows. This prevents light from passing through unintended areas and ensures a tightly defined measurement zone. For example, a 5 mm wide cell may have a 2 mm wide central aperture flanked by black glass.
  • Z-Dimension Consideration
    The Z-height, or the vertical position of the optical center, is often lowered in sub-micro cuvettes. Many have their center at 8.5 mm from the base (instead of the typical 15 mm) to align properly with microcell holders in standard spectrometers. Instruments often include beam-lowering adapters for this purpose.
  • Special Loading Features
    Loading tiny volumes requires precision. Many sub-micro cuvettes feature a funnel-shaped top or widened entry point to aid pipetting and reduce bubble formation. Some come with accessories like syringe adapters or miniature funnels. Once filled, the cells are typically sealed with micro-stoppers or films to prevent evaporation.
sub micro cuvette features

🛠️ Fabrication & Customization

  • Precision Micro Milling and Bonding
    Qvarz creates these cells by milling a cavity into a quartz substrate and bonding a transparent window plate over it. For example, a 2 mm × 10 mm trough can be cut into a quartz block and sealed with a flat quartz lid. The bonding process (optical epoxy or fusion) ensures the cell is leak-proof and optically sound.
  • Black Quartz Integration
    To enhance measurement precision, black quartz inserts are often used to form the chamber walls. These inserts create an isolated “light channel” that minimizes stray light. The materials used are chemically inert and do not contaminate the sample.
  • Ultrashort Path Options
    Some designs reduce the optical path even further—down to 1–2 mm. These ultrashort-path cuvettes may hold only 5–10 µL. Qvarz achieves this by polishing extremely thin spacers and precisely aligning window pieces, assembling them into a tightly controlled sandwich-like structure.
  • Customization
    Qvarz supports full customization of volume, dimensions, aperture size, and Z-height. Cells can be made to fit specific holders, autosamplers, or optical setups. Requests like “fit a certain micro autosampler” or “custom aperture width” are regularly accommodated.

💡 Typical Use Cases

  • DNA/RNA and Protein Quantification
    In genetic and protein assays, sample volume is often limited. Sub-micro cuvettes enable accurate absorbance measurements (e.g., 260 nm for DNA) with just a few microliters of sample.
  • Pharmaceutical Compounds
    During early-stage drug discovery, researchers may have limited quantities of a compound. Sub-micro cuvettes allow full spectral analysis with minimal sample usage.
  • Enzyme Kinetics (Small Volume)
    For enzyme assays, especially when reagents are expensive, sub-micro cuvettes enable testing with just 100 µL instead of several milliliters. When Z-height alignment is correct, kinetic readings remain just as precise.
  • Medical Diagnostics
    In neonatal or microsample diagnostics, sub-micro cuvettes are essential. Tests such as bilirubin or glucose assays benefit from minimal blood volume requirements and work well with cuvette-based analyzers.
  • Industrial Quality Control
    When testing costly materials (e.g., pharmaceutical intermediates, dyes, or specialty chemicals), sub-micro cuvettes help conserve product while providing accurate UV-Vis or absorbance readings.
sub micro cuvette applications

⚙️ Instrument Compatibility

  • Micro Cell Adapters
    Most modern spectrophotometers include adapters that lower the optical beam height to match microcell Z-dimensions (e.g., 8.5 mm). Qvarz designs its sub-micro cuvettes to work seamlessly with these adapters—commonly found in Agilent, Shimadzu, and similar systems.
  • Dedicated Microvolume Instruments
    Sub-micro cuvettes are also used in instruments purpose-built for low-volume work. These instruments typically accept cuvettes with standard external dimensions (12.5 mm square) and only require proper Z-height alignment.
  • Beam Geometry
    With narrow apertures, alignment of the optical beam is critical. Most modern instruments have a beam spot small enough (2–3 mm) to pass cleanly through the microcell. Many devices also allow beam shaping or focusing for optimal alignment.
  • Cleaning and Handling
    Due to the small internal volume, these cuvettes require careful handling—air bubbles can disrupt results, and proper filling techniques are important. While automated instruments may need configuration adjustments, manual measurements are straightforward when the microcell is placed in the correct holder. If the path length differs from 10 mm, instrument settings should be updated to ensure correct concentration readings.

💧 Single Channel Flow Through Cuvettes

Single channel flow through cuvettes are flow cells that feature one continuous internal passage for a sample stream to pass through an optical measurement zone. Unlike multi-channel designs, a single channel cell is dedicated to handling one fluid stream at a time. This is the standard format used in flow-based spectroscopy systems: one inlet, one outlet, and one optical path. These cuvettes are ideal for real-time monitoring of a sample as it flows, distinguishing them from more complex designs like split-flow or tandem sample-reference cells.

📌 Key Features

  • One Inlet & One Outlet
    Each cell is equipped with two ports—an inlet and an outlet. Fluid enters, flows through the defined optical channel, and exits. No branching or mixing occurs inside; the channel is singular and continuous.
  • Uniform Optical Path
    The optical section of the channel maintains a consistent geometry (e.g., rectangular cross-section), ensuring that every part of the flowing sample encounters the same optical conditions. This uniformity leads to accurate, representative absorbance or transmission readings.
  • Low Dead Volume
    Designed with efficiency in mind, these cells minimize dead volume, allowing fresh sample to displace old content quickly. This leads to fast response times, which is especially valuable when switching sample types.
  • Easy Flushing and Cleaning
    The simplicity of the single channel means there are no hidden recesses. Flushing with cleaning solution thoroughly cleans all wetted surfaces, reducing the chance of carryover or contamination.

🛠️ Fabrication & Customization

  • Simple Channel Design
    The core design is a straightforward single passage, either linear or slightly curved to optimize flow or path length. Qvarz typically carves or molds this channel in quartz and bonds optical windows as needed.
  • Polished Channel Walls
    The inner surfaces—particularly in the optical zone—are polished to enhance flow, avoid sample adhesion, and reduce light scattering. This ensures optical clarity and laminar flow.
  • Alignment of Ports
    Inlet and outlet ports are carefully aligned with the flow path. Whether positioned axially (straight-through) or orthogonally (L-shaped), the ports are placed to maintain smooth fluid entry and exit.
  • Customization Options
    Users can specify path length, internal cross-section, and connector type. For example, a 2 mm path for high-absorbance applications, or a larger channel for greater signal strength. Connector styles (Luer, threaded, screw-fit) are matched to the user’s instrument or system.
flow through cuvettes features

💡 Typical Use Cases

  • Standard UV-Vis Flow Measurements
    Ideal for measuring flowing samples in UV-Vis applications such as HPLC eluates, reaction monitoring, or flow injection analysis. Each cuvette handles one sample at a time for straightforward data acquisition.
  • Automated Analyzers
    Common in clinical and environmental instruments, single channel flow cells allow for sequential sample processing. Each new sample pushes the previous one out, enabling automation-friendly operation.
  • Inline Process Monitoring
    In industrial settings, these cuvettes are built into pipelines for continuous real-time monitoring of properties like dye concentration or chemical absorbance in process streams.
  • Research Kinetic Experiments
    Frequently paired with stopped-flow apparatus, single channel cells allow researchers to observe rapid reaction kinetics as reagents mix and flow through the optical path.

⚙️ Instrument Compatibility

  • One-Channel Instruments
    Most spectroscopic systems are built for single-sample readings, making single channel cuvettes the default. Even dual-beam instruments typically use two separate single channel cells—one for sample and one for reference.
  • Plumbing Integration
    These cells come with two connection points ready for fluidic integration. Instruments often include pre-positioned tubing or fittings that align directly with Qvarz’s flow cell ports, particularly in HPLC detectors.
  • Data Interpretation
    Because only one sample flows through at a time, there’s no need for signal separation. Instruments read directly from a single optical path, ensuring high compatibility and simple analysis.
  • Maintenance and Swap
    Most instruments support quick installation and removal of flow cells for cleaning or replacement. Qvarz builds its cells to match standard form factors (dimensions, notches, etc.) or provides custom shapes as needed to fit specific instrument mounts.

🔁 Reflection Measurement Cells

Reflection measurement cells are specialized cuvettes designed for optical experiments that involve measuring reflected or scattered light rather than direct transmission. These are essential in applications like turbidity assessment, back-reflection setups, or light scattering studies.

Many designs are cylindrical, which helps promote even scattering and avoid angular bias. Some variants include an internal mirror to reflect light back through the sample, effectively doubling the path length or enabling 180° measurements. These are also referred to as scattering cells or turbidimeter cells and are intended specifically for non-transmission optical geometries.

📌 Key Features

  • Cylindrical Shape
    These cells often have a round body, sometimes with flat optical windows on both ends. This geometry evenly distributes scattered light and eliminates corners where light might escape or reflect inconsistently—an issue with square cells.
  • Optional Mirror Element
    Some designs incorporate an internal mirror. This can reflect incoming light back through the sample, doubling the effective path length—especially useful in low-concentration measurements like certain IR or colorimetric setups. Mirrors may be metal or coated glass and are sealed for durability.
  • Multiple Detection Ports
    A reflection cell may include multiple optical access points. For example, one window for light entry, and others at 90° or 180° for detectors. Some models feature masking bands to control angles of detection precisely.
  • Thicker Path/Wall for Scattering
    These cells are typically bulkier. Thicker walls and wider diameters allow for better light interaction in scattering studies and provide a larger sampling volume, improving measurement accuracy for particulate media.
reflection measurement cells features

🛠️ Fabrication & Customization

  • Cylinder Fabrication
    Qvarz crafts these cells by boring quartz tubes or rods, then polishing both inner and outer surfaces to high optical clarity. Flat end windows, when used, are fused or glued perpendicular to the cylinder axis for optimal beam alignment.
  • Incorporating Mirrors
    Mirrors can be deposited directly onto internal surfaces or added as sealed inserts. In aqueous systems, mirrors are often isolated behind a transparent barrier to prevent corrosion while still enabling reflection.
  • Black Out and Masking
    To limit stray light, black coatings or opaque quartz elements can be applied. Qvarz may black out all sides except a designated observation window, ensuring measurement accuracy by controlling reflection angles.
  • Precision Path Control
    When mirrors are used, the exact distance from the window to the mirror is calibrated, factoring in optical parameters like refractive index. For multi-angle setups, the placement of side windows is measured with high precision to match instrument configurations.

💡 Typical Use Cases

  • Turbidity Measurements
    In water quality applications, turbidimeters rely on cylindrical cells to provide a clear scattering environment. A LED sends light through the sample, and a side detector at 90° captures the scattered signal.
  • Nephelometry and Light Scattering
    These cells are valuable in colloid and nanoparticle research. Reflection cuvettes can capture scattered light at various angles, including in dynamic light scattering (DLS) setups, which require consistent sample geometry.
  • Back-Reflectance Absorbance
    Some low-concentration UV-Vis systems use mirror-equipped cuvettes to reflect light back through the sample, doubling sensitivity. Such configurations are also found in gas analysis or trace liquid detection.
  • Fluorescence & Raman in Cylinders
    Cylindrical cells can be used to manage scattered excitation light in fluorescence or Raman spectroscopy. Their shape helps reduce internal reflection noise, especially in turbid biological samples.

⚙️ Instrument Compatibility

  • Dedicated Instruments
    Many turbidity meters and reflection readers require round cells—typically 19 mm or 25 mm in diameter. Qvarz matches these sizes, ensuring their reflection cells fit into standard holders.
  • Spectrophotometer Use
    Although less common, cylindrical cells can be used in standard spectrophotometers with proper adapters. Polarimeters also often use cylindrical cells with flat ends, which Qvarz supports.
  • Angle-Specific Mounting
    For multi-angle analysis, instruments must match the cell’s detection window geometry. Qvarz ensures their cells meet these angle requirements—whether for 90° detection in a turbidity meter or custom 45°/180° placements.
  • Handling Mirrors
    Instruments using mirror-equipped cells may need calibration or reflectance mode activation. These cells can be used in standard holders if their outer dimensions align with common sizes like 10 mm square. For custom setups, Qvarz can ensure proper mirror placement and alignment guidance.

🧩 Non-Stock Customizable Cuvettes

At Qvarz, we welcome custom cuvette requests—whether you need a slight modification to a standard design or an entirely new cell configuration. Our non-stock customizable cuvettes are built to order, crafted specifically to your experimental requirements. From unconventional shapes to specialized materials, we work with you to fabricate the precise cell you need—no matter how specific or novel your design may be.

Whether you’re developing a new analytical technique, working with challenging conditions, or reviving an obsolete instrument, we’re here to build exactly what your science demands.

⚒️ Customization Options

custom cuvette design
  • Wide Range of Path Lengths
    We can fabricate cuvettes with path lengths far beyond the typical 1–100 mm range. Need an ultra-short 0.01 mm path for highly absorbing samples? Or a long 100 mm cell for trace analysis? We adjust internal dimensions precisely to meet your optical and volumetric needs.
  • Diverse Geometries
    We offer more than just rectangles. Choose from cylindrical, square, triangular, wedge, trapezoidal, L-shaped, or multi-chamber designs. We can even combine features—like integrating a mirror into a flow cell or creating a spherical cavity for 360° access.
  • Material Flexibility
    While UV-grade quartz is our standard, we also fabricate using IR-grade quartz, fused silica, sapphire, optical glass, and even specialty plastics. Depending on your required spectral range—from deep UV to far IR—we select and test the appropriate materials for chemical compatibility and optical performance.
  • Custom Closures and Ports
    Choose from screw caps, septum tops, stoppers, built-in valves, luer-lock ports, or temperature-controlled jackets. Need a side arm for gas purging? A handle for radioactive materials? We’ve done it. Let us know what your setup requires.
  • Extreme Precision
    If your method demands tolerances as tight as ±0.001 mm, we can deliver. Every custom cell is verified for path length, optical window alignment, and transmission. High precision is built into every step—from grinding to inspection.

🛠️ What We Excel At

custom cuvette manufacturing
  • Monolithic and Fused Construction
    We specialize in direct fusion techniques—joining quartz parts by heat, without adhesives. This results in optically clean, chemically resistant, and structurally durable cells that meet the most rigorous lab requirements.
  • Collaborative Design Process
    You can come to us with a sketch, CAD file, or even just an idea. Our engineers work directly with you to develop feasible dimensions, tolerances, and material strategies. We’ll advise what’s practical and what’s optimal.
  • Broad Spectrum Performance
    High-grade quartz cells transmit from ~190 nm (UV) to 3,500 nm (IR). If your application is wavelength-sensitive, we ensure you get materials and coatings that preserve transmission without distortion.
    • Rapid Prototyping and Small Batches
      We don’t require large minimums. We support one-off builds, fast prototypes, and iterative designs. Our agile process means your first unit can become a production model—or remain a unique solution just for you.

🔍 Where Custom Cuvettes Are Used

  • New Instrument Development
    Engineers designing novel spectrometers often require unique cuvettes with integrated features, like a dual-chamber reference/sample cell. We support innovation with tailored components.
  • Extreme Environments
    For high-pressure, high-temperature, or chemically aggressive environments, we build cells with sapphire windows, gold coatings, or corrosion-resistant seals. These go where standard glass cannot.
  • Hybrid Analytical Techniques
    Need spectroscopy plus electrochemistry? Or imaging plus absorbance? We can add electrodes, optically thick ports, and camera windows to your custom design.
  • Educational or Demonstration Tools
    Oversized cuvettes for classrooms, clear prism cells to teach optical paths—whatever helps make science more visible, we’ll build it.
  • Reproducing Discontinued Parts
    Have a vintage instrument with an irreplaceable cuvette? We’ll reverse-engineer it from your sample or spec and recreate it, even when OEMs no longer support the model.

🧪 Instrument Compatibility

  • Made-to-Fit Designs
    Every custom cuvette is engineered to fit your specific instrument. From polarimeters to microfluidic devices, we match holders, Z-heights, and optical alignments to your hardware.
  • Specification Review
    Send us your instrument name or holder drawing. We’ll make sure your custom cuvette fits mechanically, optically, and functionally—no trial and error required.
  • Cross-Platform Integration
    We’ve made cuvettes for spectrophotometers, fluorimeters, circular dichroism setups, Raman systems, synchrotron beamlines, and more. Whatever your instrument, we can make it cuvette-compatible.
  • Adapter Assistance
    If your new cuvette needs an adapter for mounting or centering, we’ll help you source or design one. Our goal: your custom cell should fit your setup without needing a major reconfiguration.

🧾 Summary: Qvarz’s Custom Cuvette Capabilities

Qvarz is deeply committed to supporting scientific innovation by offering an extensive range of customizable cuvette solutions beyond our standard catalog. Whether you require a minor adjustment to a common design or an entirely new cell concept, we provide both the expertise and flexibility to bring it to life.

Our non-stock custom cuvettes are made-to-order based on your precise experimental needs. We accommodate:

  • Unconventional geometries (e.g., triangular, wedge, cylindrical, L-shaped)
  • Broad path length ranges (from 0.01 mm ultra-short to over 100 mm)
  • Diverse materials (UV quartz, IR quartz, fused silica, sapphire, special glass or plastics)
  • Custom ports and closures (screw caps, septa, stoppers, valves, side arms, etc.)
  • Integrated functions (mirrors, filters, electrodes, temperature jackets)

Every Qvarz custom build goes through engineering consultation, precision fabrication, and rigorous inspection to ensure it meets the highest standards of performance and durability. Our techniques—including monolithic quartz fusion and micron-level polishing—enable us to deliver cuvettes that perform reliably under extreme conditions and exacting tolerances.

Use cases span from prototype development and hybrid analytical techniques to legacy part replacement and educational demonstration tools. We support a wide range of instruments—UV-Vis, fluorescence, CD, Raman, laser optics, and even synchrotron beamlines—and will help ensure physical and optical compatibility through tailored sizing or adapter guidance.

At Qvarz, customization isn’t an exception—it’s part of what we do best. Whether you’re an industrial lab, academic group, or instrument manufacturer, we’re here to make sure your optical cell fits your science—perfectly.